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Identification of novel risk and prognostic biomarkers may enable an individualized treatment pathway for patients with DPN from a potentially disease-modifying perspective, and provide onward opportunities for novel treatments that would be efficacious in early stages of DPN, and alter the natural course of the disease

Further Reading For additional peer-reviewed research, see: HPLC purity analysis

Sardana K, Sachdeva S

However, one should also keep in mind, that p53, generally activated in cellular stress controls, is also involvedbesides controlling the above mentioned metabolic pathwaysin other cellular key processes, like apoptosis, autophagy and cell proliferation through inhibition of Akt and mTOR (Liang et al., 2013)