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Different from traditional external stimuli-triggered ROS generation strategies (e.g., CDT, SDT, and PDT) that rely on restricted intratumoral substrates such as H 2 O 2 and O 2 , our DBG hydrogel scaffold could produce abundant ROS by piezoelectrolysis of endogenous H 2 O driven by US irradiation

Cellular Stress Resistance In preclinical models, MOTS-c has also been shown to help cells tolerate metabolic and oxidative stress, which is part of the basis for interest in its potential role in aging and age-related disease

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45 Clinicians should not limit the use of GLP-1 receptor agonists and deny potential medical benefits to patients because of a history of pancreatitis or a likelihood of developing pancreatitis