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Discussion We demonstrated in the first part of the present work that both glutathione trisulfide (GSSSG) and lipoic acid trisulfide (LASSS) have potent redox characteristics that prevent nitration of Y198 and Y250 of the HGF -chain, thereby preserving the ability of HGF to bind to the receptor c-met and hence activate myogenic stem satellite cells in vitro (Figure 1b-d, and Figure 1e left column)

J Inherit Metab Dis 33(Suppl 3):S349-353

A substantial body of research has established the critical involvement of epigenetic processes in gene expression regulation, DNA damage repair, and cell cycle control and aging, highlighting their fundamental importance in molecular biology and genetics (33-35)