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doi: 10.1016/j.mam.2020.100889 28 ZhaoSChenFYinQWangDHanWZhangY

The N-methyl-d-aspartic acid receptor antagonist memantine ameliorates and delays the development of arthritis by enhancing regulatory T cells

10.1093/brain/awt023 119

8.2 Blood and CSF biomarkers Once considered a mere waste product of metabolism, L-lactate is now acknowledged for its various physiological functions in the central nervous system, such as modulating neuronal activity and ensuring energy balance (140, 141)