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The failure of these mitochondrial complexes in brain tissue is also expected to increase ROS production leading to further localized cellular damage

SLC7A11 disruption in PDAC cell lines strongly affects their amino acid and redox balance, and thus suppresses in vitro and delays in vivo their proliferative phenotype ( in vivo SLC7A11 knock out PDAC cells grew normally

HGF increased the adhesion of c-MET-positive B cell lymphoma cells to fibronectin and collagen, mediated via 1-integrin, and furthermore, promoted migration and invasion