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The thioredoxin reductase/thioredoxin (TRXR/TRX) is a major cellular redox system, which in response to oxidative stress activates the mitogen-activate-proteins-kinases (MAPK) anti-inflammatory and antiapoptotic pathways

Bone cells arent solely studied in isolation in the lab as both local and systemic factors play an important role in their function, so its important to unpick the multitude of biological factors that can affect their proliferation, says Dr Pablo Roman-Garcia, a first author from the Wellcome Trust Sanger Institute

Magdalena R, Ferrada L, Ramrez E, et al

By then, homesteaders occupied the property, some of them for a generation