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2009;89(2):693S-696S

Despite significant progress in clinical RNAi drug development, there remains considerable room for improvement in pharmacokinetics, pharmacodynamics, and strategies to mitigate toxicity (Setten et al., 2019)

Vitamin B12 deficiency is not the only serious side effect of nitrous oxide use, so recreational users should monitor their health and watch for side effects like frostbite, signs of poisoning, or seizures

Despite these limitations, the guidelines do highlight the importance of a symptom-based approach and prioritise critical research initiatives to address many of the current shortcomings associated with the patient journey