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This substantial deacetylation is the reason that high plasma levels of acetyl-l-carnitine are not observed after its oral intake, unlike after parenteral administration, during which the substance bypasses the gut and enters the bloodstream directly

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Phosphorylation of mouse eIF4EBP1 at residues T36/45 or of eIF4EBP2 at T37/46 by mTORC1 causes dissociation from eIF4E, allowing incorporation into the eIF4F complex [79]

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