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PMID: 20 AdamsHCStevenaertFKrejcikJVan Der BorghtKSmetsTBaldJet al

Lilly redesignated the compound as LY3502970 and later assigned the international nonproprietary name orforglipron

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This small molecule compound represents a selective inhibitor of NNMT, an enzyme that methylates nicotinamide (a form of vitamin B3) to produce 1-methylnicotinamide (1-MNA)