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Green cardamom supplementation improves serum irisin, glucose indices, and lipid profiles in overweight or obese non-alcoholic fatty liver disease patients: A double-blind randomized placebo-controlled clinical trial

Despite the limitations of this small study, its probably wise for women with a history of heart disease to proceed with caution when practicing cold exposure therapy, and its probably best avoided for those who have vascular conditions that affect the digits, like Raynauds disease