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Clostridium difficile has two parallel and essential Sec secretion systems

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They received 50, 150, or 300 mg canakinumab, or placebo as subcutaneous injections every three months for a median of 3.7 years

PLoS ONE 8:e82105 Lamhonwah AM, Hawkins CE, Tam C, Wong J, Mai L, Tein I (2008) Expression patterns of the organic cation/carnitine transporter family in adult murine brain