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doi: 10.1016/j.cellsig.2011.12.006 28 Lopes-PacienciaSSaint-GermainERowellM-CRuizAFKalegariPFerbeyreG

According to a 2019 study, declines in estradiol as women transition through menopause led to elevations in homocysteine, contributing to endothelial dysfunction