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4 Cantuti-CastelvetriL.FitznerD.Bosch-QueraltM.WeilM.-T.SuM.SenP.et al (2018)

Additional toxic effects include impaired hepatic ammonia detoxification, reduced liver ATP levels, an increased NADH/NAD + ratio, and mitochondrial dysfunction with impaired pyruvate carboxylation (Moreira et al., 2022)