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It has been shown that apoptosis follows extrinsic or intrinsic pathways depending on the signal that initiates it (Elmore, 2007)

ACS Appl Bio Mater

13 C NMR (100 MHz, Chloroform-d) = 163.0, 162.5, 149.3, 146.8, 138.4, 125.7, 124.7, 115.0, 114.8, 65.6, 59.4, 32.0

Administration ofthe ROS inhibitor N- acetylcysteine (NAC) partially restored GSH, attenuated ROS accumulation, and modestly alleviated Gln-deprivation-induced growth inhibition (Fig