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For example, in one study that used middle cerebral artery occlusion (MCAO) to explore the effects of Cyn in cerebral ischemiareperfusion (I/R), Cyn induced the activation of Nrf2 and peroxisome proliferative activated receptor (PPAR), contributing to the inhibition of the NF-B inflammatory pathway and potentially exerting antioxidant effects, thereby attenuating neuroinflammation and cerebral infarction (Li et al., 2019)

Referenced with permission from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Small Cell Lung Cancer V.1.2026

As the first line of defense, epithelial cells utilize specific PRRs to recognize C

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