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Weeks Tirzepatide dose Notes 14 2.5 mg Initiation only (not for glucose/weight effect) 58 5 mg First maintenance option 912 7.5 mg Increase as tolerated 1316 10 mg Maintenance option 1720 12.5 mg Increase as tolerated 21+ 15 mg (max) Maximum maintenance dose These steps follow the Mounjaro FDA label and Zepbound FDA label

3,4 Smoking, older age, obesity and metabolic syndrome, family history, a sedentary lifestyle, infection, and certain health conditions and medications increase the risk of developing an abnormal blood clot

Table 1 shows baseline CNS-VS test results, with treatment dates shown in Table 2

This combined approach allows researchers to examine potential synergistic effects beyond single-pathway activation