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Its clinical program in the late 2000s was built around large, rigorously controlled trials with a hard imaging endpoint (visceral adipose tissue measured by CT), and it culminated in FDA approval in 2010

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[4] In other words, most patients with detectable anti-sermorelin antibodies continue to respond to therapy, and the antibodies may disappear over time even if treatment continues

The subjects receiving GHRH experienced a longer period of rapid eye movement (REM) sleep and increased slow-wave sleep (SWS), among other benefits