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Fourth, combination therapy: co-delivery systems (e.g., lipid-based vesicles co-encapsulating anti-inflammatory and urate-lowering agents) synergistically address inflammation and hyperuricemia, simplifying treatment regimens (Li et al., 2023)

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Antioxidant mechanisms The antioxidant property of GSH is mostly attributed to GSH peroxidase-catalyzed reactions, where hydrogen peroxide and lipid peroxide are reduced while GSH is oxidized to GSSG

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