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Common symptoms include: abdominal swelling, distension or bloating, diarrhea, enlarged, fatty liver, fatigue, frequent infections, generalized swelling, hair and nail changes, including brittle, reddish hair and ridged nails that are thin and soft, Irritability, muscle wasting, skin changes, including pigment loss, red or purple patches, peeling, cracking, skin sloughing, and the development of sores, slowed growth leading to short stature, weight loss

Oh IS, Shimizu H, Satoh T, Okada S, Adachi S, Inoue K, et al

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