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Aminoglycosides enter cochlear hair cells primarily through MET channels rather than classical drug transporters ( Age-related vulnerabilities Pediatric populations show age-related differences in ototoxicity susceptibility, with neonates, particularly preterm neonates, facing the highest risk

By reducing the activation of these glial cells, forskolin helps to mitigate neuroinflammation

M.E.Anderson glutathion DTNB glutathione reductase glutathione recycling system

As expected, rotenone increased the production of ROS in both cell lines, but probably due to different expression of efflux pumps and therefore uncertainties in the assay (Sieprath et al