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doi:10.1083/jcb.201612069

USP2 also deubiquitinates the transferrin receptor (TFRC), enhancing TFRCs role in promoting ferroptosis

McGehee WG, Klotz TA, Epstein DJ, Rapaport SI

Consequently, contemporary medicine must concentrate on understanding the pathophysiological mechanisms driving systemic decline and on finding ways to address them