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Various stimuli, including telomere dysfunction and oxidative stress, induce cellular senescence through the p53 and Rb proteins, and senescent cells can promote disorders associated with aging or age-related diseases

doi: 10.1016/j.biopha.2023.115772 236 WangXLiuZPengPGongZHuangJPengH

What B12 deficiency does NOT cause: Male pattern baldness (androgenetic alopecia) this is DHT-driven Female pattern thinning (Ludwig-type) also androgen-driven Patchy loss (alopecia areata) autoimmune origin Receding hairline typically androgenetic Treating B12 deficiency will not reverse pattern hair loss

Clinical presentation and medical management of melioidosis in children: a 24-year prospective study in the Northern Territory of Australia and review of the literature