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GPT, also called alanine transaminase, includes the cytoplasmic GPT1 and mitochondrial GPT2 isoforms and catalyzes the reversible conversion of glutamate to pyruvate for -KG and alanine generation

The histomorphometrical analysis was applied using the ImageJ analysis tool (version 1.36, NIH, United States)

A growing number of experimental studies (in vivo or in vitro) have reported the functional changes of SNr GABAergic neurons in different types of encephalopathy or neurological diseases, especially in Parkinsons disease and epilepsy 46,47

Side effects are usually mild and temporary some patients feel slight nausea, dizziness or a headache during an IV drip, or minor tenderness at the injection site