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Acknowledgements The authors wish to acknowledge that this manuscript is derived in part from the doctoral dissertation titled Bio-Geochemistry of ovarian cancer: Role of selenium nanoparticles in treatment and copper isotopes in detection of ovarian cancer., completed by Benoit Toubhans under the supervision of R

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doi: 10.1152/physrev.00045.2009 45 FosterJANeufeldK-a

Tofogliflozin, a highly selective inhibitor of sglt2 blocks proinflammatory and proapoptotic effects of glucose overload on proximal tubular cells partly by suppressing oxidative stress generation