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Iron retardation in lysosomes protects senescent cells from ferroptosis

It has been recently shown [60] that T cells from depressed patients displayed a compromised metabolic profile accompanied by heightened gene expression of CTP1a (carnitine palmitoyltransferase 1 A), the mitochondrial enzyme responsible for ACs synthesis

Discussion Conflicting reports of human CBS oligomerisation, evidenced by a variety of biophysical and immunoblotting techniques using both recombinant and endogenous sources of the protein, have plagued the literature since its initial characterisation 10,11,20,21,22,23,33,34

TurnerTNWilfertABBakkenTEBernierRAPepperMRZhangZet al