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p = 0.053), a reduction was observed in pain over time (Numeric Pain Rating Scale, NPRS) in the intervention group, with a change score of 2 immediately post-chemotherapy and three months post-chemotherapy [OR: 0.85 (95% CI: 0.76 to 0.94

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Hirota M, Takada T, Kawarada Y, Nimura Y, Miura F, Hirata K, Mayumi T, Yoshida M, Strasberg S, Pitt H, Gadacz TR, de Santibanes E, Gouma DJ, Solomkin JS, Belghiti J, Neuhaus H, Buchler MW, Fan ST, Ker CG, Padbury RT, Liau KH, Hilvano SC, Belli G, Windsor JA, Dervenis C (2007) Diagnostic criteria and severity assessment of acute cholecystitis: Tokyo Guidelines