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Herbal medicines have been in use for over 1,000 years and are one of the most promising sources of new medicines ( G

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Susceptibility to gut leakiness: a possible mechanism for endotoxaemia in non-alcoholic steatohepatitis

It was reported that DRAM1 aggravates the intestinal epithelium damage of IBD patients and mouse models through increasing the activation of JNK/c-Jun pathway, but the expression of DRAM1 shows no significant change in the intestinal tissues with acute inflammation (Zhang et al., 2021)