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Hot flashes and mood changes often get the spotlight, for example, but estrogen also plays an important role in connective tissue health and inflammation

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We identified AEP trails as having distinct morphology (distinguishable from membrane vesicles and tubule-like outer membrane protrusions, as well as the S-motility-related EPS fibrils) in the TEM, and by their pH sensitivity, as treatment with acidic stains (un-buffered uranyl acetate (UA), pH 4.5 or SiPTA at pH 4.0) removed slime trails (but not other membrane components, i.e., vesicles) from grids, while neutral stains (SiPTA at pH 7.0) did not (Fig