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Concurrently, the emergence of molecularly intelligent photosensitizers that change their photophysical or chemical behavior in response to lesion-specific cues (pH, enzymes, redox) exemplifies how analyte-sensing functionality can be built directly into imaging-therapeutic agents

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On inquiry, the majority of patients (45%) who defaulted in regular follow-up reported a belief that the disease would not spread, while an additional 21.2% reported unwillingness to spend money on conditions that did not cause symptoms

Biol Chem 401(11):12571271