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S.AgrawalR.RaghuwanshiR.JainP

Therefore, ubiquitination is not only important for protein degradation, but is also implicated in non-proteolytic functions, such as endocytosis, protein-protein interaction, intracellular trafficking, inflammatory signaling, autophagy, and DNA repair (Grabbe et al., 2011

This strategy is commonly used in site-specific cross-linking with bis or tri-electrophilic linkers and has proven to be a powerful method for reinforcing protein secondary and tertiary structures 37,38

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