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10.3389/fimmu.2017.01678 Front Immunol

Nevertheless, despite the FDA's repeated calls to criminalize kratom under the Control Substances Act, there is no proof that kratom use has caused significant health problems such as those of classical opioids (9)

2,11 Therefore, the AAN states, There is insufficient evidence to make recommendations regarding the use of facial nerve decompression to improve facial functional outcomes(level U recommendation)