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A recent study (48) has shown that PI3K activating its downstream effector protein kinase B (Akt) can improve hippocampal brain injuries and restore neuronal development after neonatal HIBD, which demonstrates that the activation of PI3K/Akt pathway can promote endogenous neurogenesis induced by HIBD

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Consider the effect of an angiotensin-converting enzyme (ACE) inhibitor, such as enalapril, on ACE