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doi: 10.1111/rda.12902

For each pHLA complex, the top five models with the lowest Rosetta binding energy were selected as the final structural ensemble

In vivo, low-dose Clc (1:751:380) degraded gliadin and attenuated pathology in gliadin-fed mice, reducing villus atrophy, inflammation, antibody responses, and gluten-induced dysbiosis, while restoring immune-regulatory markers and microbial metabolic pathways