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Notably, the ephrin pathway, which regulates cell signaling, cellular morphology, stem cell niche maintenance, axon guidance, and energy metabolism was found to be upregulated in ME/CFS patients

But if not, I personally like to add another 5% more thinner

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Ohno Y, Sone M, Inagaki N, Yamasaki T, Ogawa O, Takeda Y, et al