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Targeting tacrolimus to deeper layers of skin with improved safety for treatment of atopic dermatitis

In the landmark SURMOUNT-1 trial, participants receiving the highest dose of tirzepatide lost an average of 22.5% of their body weight over 72 weeks, making it one of the most effective pharmaceutical weight loss interventions available (Jastreboff et al., 2022, New England Journal of Medicine )

Potential Benefits in Research Skin & Tissue Research Enhanced collagen and elastin production Improved skin firmness and elasticity Wound healing acceleration Reduction in visible aging markers Regenerative Properties Tissue remodeling and repair Blood vessel formation (angiogenesis) Nerve tissue regeneration support Hair follicle stimulation Anti-Inflammatory Effects Reduction in inflammatory cytokines Enhanced antioxidant enzyme activity Protection against oxidative damage Modulation of immune responses Safety Profile Important: These side effects are reported from research studies and may vary by individual, dosage, and protocol

Three or more freeze-thaw cycles on a reconstituted peptide will produce measurable loss of activity in most sequences