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The peptide binds GHRH receptors on anterior pituitary somatotroph cells, activates adenylyl cyclase to increase intracellular cAMP, enhances transcription of the GH gene, and stimulates exocytosis of stored GH from secretory granules

Glutathioneis the master detoxifier and the bodys main endogenous antioxidant.* Toxins are linked to glutathione, which then carries them into the bile and the stool, and out of the body

These redox-sensitive transcription factors activated by ROS can enhance the gene expression of proinflammatory factors [tumor necrosis factor- (TNF-), interleukin-1 (IL-1), and interleukin-6 (IL-6)], proinflammatory enzymes [inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2)], adhesion molecules [intercellular adhesion molecular-1 (ICAM), vascular cell adhesion molecule (VCAM)], and antioxidant enzymes [Mn-SOD, NOQ-1 and glutathione peroxidase (Gpx)], one of the primary steps in the formation and development of lesions

Can nicotinamide adenine dinucleotide (NAD(+)) and sirtuins be Harnessed to improve mare fertility