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Autophagy is a stress-induced protective mechanism

However, due to the narrow time window of 46 h after stroke onset, only a small number of patients can receive efficient thrombolytic therapy

J Biol Chem 253:84338443

Dose: 2mg twice daily (4mg total) Frequency: Morning and evening Duration: 4-6 weeks maximum Rest period: Equal to cycle length Splitting doses maintains more stable plasma levels throughout the day