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Calcium channel ITPR2 and mitochondria-ER contacts promote cellular senescence and aging

Biochemistry 46, 84148424

Morphine Opioids are widely-used analgesics that bind with opioid and/or toll-like receptors (TLR) in the CNS ( Morphine exerts its effects by directly acting on the CNS with its illicit use leading to tolerance and drug dependence ( P-gp limits the net transport of several foreign substrates into the brain through active unidirectional efflux