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The diurnal oscillations of oxidative stress enzymes can directly lead to rhythmic changes in ROS

Controlled Release 2019, 303, 91100

Sikirica V, Flood E, Dietrich CN, et al

It is possible that up to 80% of the mitochondrial dysfunction in patients with both ASD and a mitochondrial disorder are acquired rather than inherited ( Table 3 Mitochondrial function biomarkers in ASD (see text for references)