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Quercetin can effectively block the release of human mast cell cytokines, helping to calm the systemic inflammatory storms that drive MCAS flares

doi: 10.3389/fmicb.2022.948770 52 DavisD

Antiapoptotic response to induced GSH depletion: involvement of heat shock proteins and NF-kappaB activation

As a matter of fact, taking into full account the intricacy of the numerous regulatory mechanisms involved in OS control as well as the complex interplay between the many events that contribute to the progressive degeneration and death of MNs, future neuroprotective pharmacological therapies will likely need to aim for an integrated treatment, acting on several levels to limit the progression of the disease