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10.1016/j.redox.2022.102537 235 WangY

With the production of adipokines and decreased activity of GPx and antioxidant capacity, the endothelium becomes deficient in nitric oxide (NO), a vasodilator, and thus promotes atherosclerotic diseases

Con: IV has the worst side effects and can include allergic reactions in extreme cases

Finally, renal tubules empty into collecting ducts , which channel the unabsorbed water and electrolytes toward the ureters and eventually the bladder