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We then examined the SPOP-mediated ubiquitination linked chain s of KCNN3, utilizing a set of ubiquitin mutants that contain a single K-R mutation in each of the seven lysines in the ubiquitin, as well as a lysine-free ubiquitin mutant(K-ALL-R) in which all lysines are replaced by arginine

However, because CD36 deletion itself fundamentally hampers baseline efferocytosis, the observed loss of protection cannot be attributed exclusively to the disruption of an RIPostC -mediated pathway