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Moreover, increased expression levels of IRF7, a transcription factor that binds to promoters on IFN type I genes, corroborates the strong induction of IFN-a and IFN- by ZIKV-infected fibroblasts

For mitochondrial targeting, the transit peptide of subunit 8 from the human cytochrome c oxidase complex was amplified from pCDNA3.1-MitoGFP, using oPM034/oPM035 as internal and oPM036/oPM037 as external primers, in a nested PCR reaction placed in one tube (Supplementary Table 3)

Conclusions Glucose does not share some of its functions in the brain with other metabolic substrates, which makes it an exclusive neurometabolite

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