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A peliminary analysis on behalf of Polish Adult Leukemia Group Jaroslaw Dybko 1 , Agnieszka Piekarska 2 , Donata Urbaniak-Kujda 3 , Monika Biernat 3 , Magdalena Dutka 2 , Alicja Sadowska-Klasa 2 , Sebastian Giebel 4 , Tomasz Wrbel 3 , Kazimierz Kuliczkowski 3 , Lidia Gil 5 1 2 3 3 2 2 4 3 3 5 1 Wroclaw Medical University, Department of Internal and Occupational Diseases, Hypertension and Clinical Oncology, Wroclaw, Poland

Targeting histone modifications Histone modification drugs are capable of rectifying dysregulated histone modification patterns within malignant cells to suppress the aberrant gene transcriptions associated with oncogenesis