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[DOI] [PubMed] [Google Scholar] 28.Smith M.H., Bhattacharyya I., Cohen D.M., Islam N.M., Fitzpatrick S.G., Montague L.J., Damm D.D., Fowler C.B

Currently, there is no scientific basis for performing genetic testing in AMS patients except in research protocols.18,58,59 CONCLUSION AMS demonstrably increases the risk of developing melanoma, a malignant neoplasm for which incidence have increased significantly in recent decades and for which early diagnosis is of great importance in the prognosis of the disease.4,59 The identification of patients with AMS, the main clinical risk factor, allows them to be included in short and long term monitoring programs, aimed at early detection of suspicious lesions and the consequent reduction in mortality associated with advanced melanoma.42 In addition, a prevention program could contribute to increased awareness and changes in risk behavior, minimizing the environmental risk not only for patients but also for their families

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Although the pathogenesis of nevi remains unknown, it has been suggested that the lesions are benign neoplasms