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Some of those proteins, of course, are related to the production of melanin

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( f-g ) Cells were treated with the IDH1 inhibitor ( f ) or cultured under glutamine starvation ( g ) and treated cisplatin (Cis) alone and in combination with or without l-carnitine supplementation (n = 4 technical replicates representative from 3 independent experiments)

As these recent studies show that higher oral doses of L-carnitine can promote atherogenesis and CVD risk, these findings also support our contention of limiting the oral maintenance dosing of L-carnitine to 3 g per day in the setting of acute MI and call for further investigation on the long-term risks of chronic L-carnitine supplementation in CVD patients