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Coadministration of huperzine A and ligustrazine phosphate effectively reverses scopolamine-induced amnesia in rats

Galkin VE, Orlova A, Egelman EH

doi: 10.1016/j.xphs.2016.08.020

What it's studied for In animals and in cells, dihexa has been looked at for: Memory and learning in rodents mostly the Morris water maze, a test where a rat has to remember where a hidden platform is Models of Alzheimer's disease for example, in genetically modified mice bred to develop Alzheimer's-like brain changes Models of Parkinson's disease and motor problems Growing new synapses in hippocampal cells in a dish There's also a genuinely mundane use worth knowing about, because it's revealing: dihexa shows up in stem cell laboratories as a reagent a cheap chemical stand-in for an expensive growth factor, used to help turn stem cells into liver cells in a dish