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Pipeline: what is coming next The obesity pipeline is unusually crowded, and the direction is toward oral dosing and additional hormone targets

Monitoring commonly includes pain evaluations, neurological assessments, inflammatory markers, complete blood counts, and quality-of-life measurements

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This discrepancy may arise in part because the majority of B12 in serum is bound to the transport protein haptocorrin which is not physiologically active and thus unavailable for B12-dependent enzymatic reactions in cells (Green et al., 2017)