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Description

To ascertain hypoxic culture conditions, we used a standard color assay (viz., methylene blue reduction) 35

The following examples are offered for illustrative purposes only, and are not intended to limit the scope of the present invention in any way

Loss of BMAL1 enhances nuclear factor kappa-light-chain-enhancer of activated b cells (NF-B) activation and prolongs inflammatory gene transcription in both macrophages and renal epithelial cells ( In the kidney, circadian misalignmentinduced by altered light-dark cycles or genetic manipulationleads to increased macrophage infiltration, tubular injury, and glomerular inflammation