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10.1073/pnas.0805779105 Proc

Methods This review is based on literature searches performed in the PubMed database in October 2020 using the search terms irritable bowel syndrome, functional bowel disorder, diarrhea, therapy, treatment, randomized clinical trial, probiotics, antibiotics, antispasmodics, peppermint oil, herbal, plant-derived, antidepressants, loperamide, cholestyramine, alosetron, ramosetron, ondansetron, rifaximin, eluxadoline, xyloglucan, crofelemer

Second, the outcome of VR may be a subject of great variability as it relies on several factors, including patients age, varicocele grade, testicular volume, pretreatment semen parameters, and reproductive hormone levels [26,27,28]